Bruno Christ/Jana Oerlecke/Peggy Stock: Animal Models for Stem Cell Therapy (gebundenes Buch)

InhaltsangabePART I  INTRODUCTION 1          Stem Cells--Are We Ready for Therapy?            Insa Schröder 2          Aurigon's Point of View on the Safety Assessment of Cell Based Therapies - An Experience Based on the Participation in 15 ATMPs Projects            Emmanuelle Cornali            PART II          LIVER DISEASES3          Pre-Conditioning of the Liver for Efficient Repopulation by Primary Hepatocyte Transplants            Petra Krause, Margret Rave-Fraenk, Hans Christiansen, Sarah Koenig4          Age-Dependent Hepatocyte Transplantation for Functional Liver Tissue Reconstitution            Peggy Stock    5          Treatment of NASH with Human Mesenchymal Stem Cells in the Immunodeficient Mouse          Sandra Winkler, Bruno Christ            6          The in vivo Evaluation of the Therapeutic Potential of Human Adipose Tissue-Derived Mesenchymal Stem Cells for Acute Liver Disease Takeshi Katsuda, Hayato Kurata, Rie Tamai, Agnieszka Banas, Tsuyoshi Ishii, Shumpei Ishikawa, and Takahiro Ochiya 7          A Mouse Model of Liver Injury to Evaluate Paracrine and Endocrine Effects of Bone Marrow Mesenchymal Stem CellsChiung-Kuei Huang, Soo Ok Lee, Jie Luo1, RongHao Wang, Qiang Dang, Chawnshang Chang   8          Animal Models to Test hiPS-Derived Hepatocytes in the Context of Inherited Metabolic Liver DiseasesMathilde Dusséaux, Sylvie Darche and Hélène Strick-Marchand     9          Support of Hepatic Regeneration by Trophic Factors from Liver-Derived Mesenchymal Stromal/Stem CellsSuomi M.G. Fouraschen, Sean R.R. Hall, Jeroen de Jonge and Luc J.W. van der Laan PART III CARDIOVASCULAR DISEASES 10        Assessment of Functional Competence of Endothelial Cells from Human Pluripotent Stem Cells in Zebrafish Embryos            Valeria V. Orlova, Yvette Drabsch, Peter ten Dijke and Christine L. Mummery11        Stem Cell Therapy for Necrotizing Enterocolitis: Innovative Techniques and Procedures for Pediatric Translational Research            Jixin Yang, Yanwei Su and Gail E. Besner    12        Exploring Mesenchymal Stem Cell-Derived Extracellular Vesicles in Acute Kidney InjuryStefania Bruno, Giovanni Camussi     13        Angiogenesic Properties of Mesenchymal Stem Cells in a Mouse Model of Limb Ischemia            Sang Won Han14        Methods to Assess Intestinal Stem Cell Activity in Response to Microbes in Drosophila melanogaster            Philip L. Houtz and Nicolas Buchon            PART IV CONNECTIVE AND CONTRACTILE TISSUE 15        Muscle Pouch Implantation: An Ectopic Bone Formation Model Greg Asatrian, Le Chang, Aaron W. James 16        Bone Defect Repair in Mice by Mesenchymal Stem Cells            Sanjay Kumar 17        Generation of Osteoporosis in Immune-Compromised Mice for Stem Cell Therapy            Reeva Aggarwal, Vincent J. Pompili and Hiranmoy Das       18        Application of Stem Cells for the Treatment of Joint Disease in Horses            Walther Brehm, Janina Burk, Uta Delling19        Adipogenic Fate Commitment of Muscle-Derived Progenitor Cells: Isolation, Culture and DifferentiationAnne-Marie Lau, Yu-Hua Tseng, and Tim J. Schulz20        Skeletal Muscle Stem Cells for Muscle RegenerationJohnny Kim and Thomas Braun            PART V          NEUROLOGICAL DISEASES 21        Bone Marrow Stromal Stem Cells Transplantation in Mice with Acute Spinal Cord Injury            Virginie Neirinckx, Bernard Rogister, Rachelle Franzen, Sabine Wislet-Gendebien 22        Histological Characterisation and Quantification of Cellular Events Following Neural and Fibroblast(-Like) Stem Cell Grafting in Healthy and Demyelinated CNS TissueJelle Praet,

In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective, and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS).  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical,  Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.